Selected Publications Funded by CIHR and Ontario Heart and Stroke Foundation.
Hu J, Mukhopadhyay A, Truesdell P, Chander H, Mukhopadhyay UK, Mak AS, Craig AW.
Cdc42-interacting protein 4 is a Src substrate that regulates invadopodia and invasiveness of breast tumors by promoting MT1-MMP endocytosis.
J.Cell Sci. (2011) 124, 1739-1751.
p53 regulation of podosome formation and cellular invasion in vascular smooth muscle cells.
Cell Adh Mgr (2011) 5, 144-149. Review.
Poon JS, Eves R, Mak AS.
Both lipid- and protein-phosphatase activities of PTEN contribute to the p53-PTEN anti-invasion pathway
Cell Cycle (2010) 9, 4450-4454.
Mukhopadhyay UK, Mooney P, Jia L, Eves R, Raptis L, Mak AS.
Doubles game: Src-Stat3 versus p53-PTEN in cellular migration and invasion.
Mol Cell Biol (2010) 30, 4980-4995.
Xiao H, Bai XH, Kapus A, Lu WY, Mak AS, Liu M.
The protein kinase C cascade regulates recruitment of matrix metalloprotease 9 to podosomes and its release and activation.
Mol Cell Biol (2010) 30, 5546-5561.
Mukhopadhyay UK, Eves R, Jia L, Mooney P, Mak A.S.
p53 suppresses Src-induced podosome and rosette formation and cellular invasiveness through the upregulation of caldesmon.
Mol Cell Biol (2009)29(11): 3088-3098.
Mukhopadhyay UK, Mak AS.
p53: is the guardian of the genome also a suppressor of cell invasion?
Cell Cycle (2009) 8(16):2481.
Xiao H, Eves R, Yeh C, Kan W, Xu F, Mak AS, Liu M.
Phorbol ester-induced podosome in human epithelial cells.
J. Cell Physiol (2009)218(2) 366-375.
Webb, B.A., Jia, L., Eves, R. and Mak, A.S.
Dissecting the functional domain requirements of cortactin in invadopodia formation.
Eur J Cell Biol (2007) 86 189-206.
Eves, R. Webb, B.A., Zhou, S. and Mak, A.S.
Caldesmon is an integral component of podosomes in vascular smooth muscle cells.
J. Cell Sci. (2006)119 1691-1702.
Webb, B.A., Zhou, Z., Eves., R., Shen, L., Jia, L. and Mak, A.S.
Phosphorylation of cortactin by p21-activated kinase.
Arch Biochem Biophys (2006) 456 183-193.
Webb,B.A. Eves,R. and Mak,A.S.
Cortactin regulates podosome formation in A7r5 vascular smooth muscle cells: the roles of functional domains.
Exp Cell Res (2006) 312:760-769.