Selected Publications Funded by CIHR and Ontario Heart and Stroke Foundation.

Hu J, Mukhopadhyay A, Truesdell P, Chander H, Mukhopadhyay UK, Mak AS, Craig AW. 
         Cdc42-interacting protein 4 is a Src substrate that regulates invadopodia and invasiveness of breast tumors by promoting MT1-MMP endocytosis.
         J.Cell Sci. (2011) 124, 1739-1751.

Mak, A.S.
         p53 regulation of podosome formation and cellular invasion in vascular smooth muscle cells.
         Cell Adh Mgr (2011) 5, 144-149. Review.

Poon JS, Eves R, Mak AS.          
         Both lipid- and protein-phosphatase activities of PTEN contribute to the p53-PTEN anti-invasion pathway
         Cell Cycle  (2010) 9, 4450-4454.

Mukhopadhyay UK, Mooney P, Jia L, Eves R, Raptis L, Mak AS.
          Doubles game: Src-Stat3 versus p53-PTEN in cellular migration and invasion.
          Mol Cell Biol
(2010) 30, 4980-4995. 

Xiao H, Bai XH, Kapus A, Lu WY, Mak AS, Liu M.       
         The protein kinase C cascade regulates recruitment of matrix metalloprotease 9 to podosomes and its release and activation.                    
          Mol Cell Biol (2010) 30, 5546-5561.

Mukhopadhyay UK, Eves R, Jia L, Mooney P, Mak A.S.          
            p53 suppresses Src-induced podosome and rosette formation and cellular invasiveness through the upregulation of caldesmon.
            Mol Cell Biol (2009)29(11): 3088-3098.     

Mukhopadhyay UK, Mak AS.
            p53: is the guardian of the genome also a suppressor of cell invasion?
            Cell Cycle (2009) 8(16):2481.            

Xiao H, Eves R, Yeh C, Kan W, Xu F, Mak AS, Liu M.
            Phorbol ester-induced podosome in human epithelial cells.
            J. Cell Physiol (2009)218(2) 366-375.         

Webb, B.A., Jia, L., Eves, R. and Mak, A.S.
           Dissecting the functional domain requirements of cortactin in invadopodia formation. 
           Eur J Cell Biol  (2007) 86 189-206. 

Eves, R. Webb, B.A., Zhou, S. and Mak, A.S.
            Caldesmon is an integral component of podosomes in vascular smooth muscle cells.
             J. Cell Sci. (2006)119 1691-1702.    

Webb, B.A., Zhou, Z., Eves., R., Shen, L., Jia, L. and Mak, A.S.
            Phosphorylation of cortactin by p21-activated kinase.
            Arch Biochem Biophys (2006) 456 183-193.

Webb,B.A. Eves,R. and Mak,A.S.
            Cortactin regulates podosome formation in A7r5 vascular smooth muscle cells: the roles of functional domains.
            Exp Cell Res (2006) 312:760-769.