Selected Publications:

Wilson LS, Elbatarny HS, Crawley SW, Bennett BM and Maurice DH, 2008, Compartmentation and compartment-specific regulation of PDE5 by protein kinase G allows selective cGMP-mediated regulation of platelet functions. Proc Natl Acad Sci USA, 105:13650-13655.

Raymond DR, Wilson LS, Carter RL and Maurice DH, 2007, Numerous distinct PKA- or EPAC-based signalling complexes allow selective phosphodiestaerase 3 and phosphodiesterase 4 coordination of cell adhesion. Cell Signal, 19:2507-2518.

Netherton SJ, Sutton JA, Wilson LS, Carter RL and Maurice DH, 2007, Both protein kinase A and exchange protein activated by cAMP coordinate adhesion of human vascular endothelial cells. Circ Res, 101:768-776.

Houslay MD, Baillie GS and Maurice DH, 2007, cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling. Circ Res, 100:950-966.

Palmer D, Jimmo SL, Raymond DR, Wilson LS, Carter RL and Maurice DH, 2007, Protein kinase A phosphorylation of human phosphodiesterase 3B promotes 14-3-3 protein binding and inhibits phosphatase-catalyzed inactivation. J Biol Chem, 282:9411-9419.

Elbatarny HS, Netherton SJ, Ovens JD, Ferguson AV and Maurice DH, 2007, Adiponectin, ghrelin and leptin differentially influence human platelet and human vascular endothelial cell functions: implication in obesity-associated cardiovascular diseases. Eur J Pharmacol, 558:7-13.

Netherton SJ and Maurice DH, 2005, Vascular endothelial cell cyclic nucleotide phosphodiesterases and regulated cell migration: implications in angiogenesis. Mol Pharmacol, 67:263-272.

Tilley DG and Maurice DH, 2005, Vascular smooth muscle cell phenotype-dependent phosphodiesterase 4D short form expression: role of differential histone acetylation on cAMP-regulated function. Mol Pharmacol, 68:596-605.

Elbatarny HS and Maurice DH, 2005, Leptin-mediated activation of human platelets: involvement of a leptin receptor and phosphodiesterase 3A-containing cellular signaling complex. Am J Physiol Endocrinol Metab, 289:E695-E702.

Maurice DH, Palmer D, Tilley DG, Dunkerley HA, Netherton SJ, Raymond DR, Elbatarny HS and Jimmo SL, 2003, Cyclic nucleotide phosphodiesterase activity, expression and targeting in cells of the cardiovascular system. Mol Pharmacol, 64:533-546.