Inka Brockhausen, Ph.D

Inka Brockhausen

Faculty Bio

The Brockhausen lab aims to understand the biochemical mechanisms underlying diseases such as inflammation, infections and cancer. Studies of the role of protein glycosylation in cell behaviour and cell death will reveal new mechanisms in cancer and inflammation. We also hope to develop novel therapeutic interventions based on our knowledge and inhibition of glycosyltransferase enzymes that glycosylate proteins in humans, and assemble the O-antigenic polysaccharides in pathogenic bacteria. Newly developed assays for glycosyltransferases help to characterize enzymes, reveal protein structure and function relationships, and design inhibitors which could 1. Reduce inflammation, 2. Reduce cancer metastasis and 3. Act as new antibiotics for Gram negative bacteria.

Last Modified: 2016-02-29