Selected Publications:

Wynick C., C. Petes, and K.Gee 2014. Interleukin-27 mediates inflammation during chronic disease. The Journal of Interferon and Cytokine Research. (10):741-9.

Gambhir V, C. Yildiz, S. Siddiqui, C. Guzzo, R. Mulder, M. Szewczuk, K. Gee, and S. Basta. 2012. TLR2 subunit agonists are superior inducers of pro-inflammatory mediators than inactivated Mycobacterium butyricum. Cellular Immunology. 280(1):101-107.

Guzzo, C., M. Jung, A. Graveline, B.W. Banfield, and K. Gee. 2012. IL-27 regulates BST-2 expression independently of type-I IFN on human monocytes and T cells. Scientific Reports 2:974.

Guzzo, C., W.M. Hopman, N.F.Che Mat, W. Wobeser, and K. Gee. 2012. IL-27-induced gene expression is downregulated in HIV-infected subjects.  PlosOne. 7(9):e45706.

Guzzo, C., A. Ayer, B Banfield, S. Basta, and K. Gee. 2012. Interleukin-27 induces TLR4 expression on human monocytes via a STAT3 and NF-kB dependent pathway. Journal of Immunology. Jan 15;188(2):864-73.

S. Abdulkhalek, S. R. Amith, S.L. Franchuk, P. Jayanth, M. Guo, T. Finlay, A.Gilmour, C.Guzzo, K. Gee, R. Beyaert, and M.R. Szewczuk. 2011. Neu1 sialidase and matrix metalloproteinase-9 cross-talk is essential for TOLL-like receptor activation and cellular signalling. Journal of Biological Chemistry. Oct 21;286(42):36532-49.

Che Mat, NF, X. Zhang, C. Guzzo, and K. Gee. 2011. IL-23-induced IL-23 receptor subunit expression is mediated by the JAK/STAT pathway in human CD4 T cells. Journal of Interferon and Cytokine Research. 2011 (4):363-71.

Finlay TM, S. Abdulkhalek, A. Gilmour, C. Guzzo, P. Jayanth, SR Amith, K. Gee, R. Beyaert, and MR Szewczuk. 2010. Thymoquinone-induced Neu4 sialidase activates NFkappaB in macrophage cells and pro-inflammatory cytokines in vivo. Glycoconj J. Aug 10. (6):583-600

Guzzo, C., N.F.Che Mat, and K. Gee. 2010. Interleukin-27 induces a STAT1- and STAT3-dependent proinflammatory cytokine and chemokine profile in human monocytes. Journal of Biological Chemistry. Aug 6;285(32):24404-11.

Guzzo, C., W.M. Hopman, N.F.Che Mat, W. Wobeser, and K. Gee. 2010. Impact of HIV infection, highly active anti-retroviral therapy, and hepatitis C co-infection on serum interleukin-27 expression. AIDS. Jun 1;24(9):1371-4.

Jayanth, P., S. R. Amith, K. Gee, and M. R. Szewczuk. 2010. Neu1 Sialidase and Matrix Metalloproteinase-9 Cross-talk is Essential for Neurotrophin Activation of Trk Receptors and cellular signaling. Cell Signal. Aug; 22(8):1193-205.

Finlay, TM, P. Jayanth, S.R. Amith, A. Gilmour, C. Guzzo, K. Gee, R. Beyaert, and M.R. Szewczuk. 2010. Thymoquinone from Nutraceutical Black Cumin Oil Activates Neu4 Sialidase in Live Macrophage, Dendritic, and Normal and Type I Sialidosis Human Fibroblast Cells via GPCR Gαi proteins and Matrix Metalloproteinase-9. Glycoconj. J. Apr; 27(3):329-48.