Selected Publications:

  1. Philbrook, N.A. and Winn, L.M. (2015) Investigating the effects of in utero benzene exposure on epigenetic modifications in maternal and fetal CD-1 mice. Toxicol. Appl. Pharmacol. (accepted)
  2. Philbrook, N.A. and Winn, L.M. (2015) Benzoquinone-mediated increased DNA damage and decreased Ogg1 gene expression are not altered by sulforaphane pretreatment in cultured CD-1 mouse fetal liver cells. (submitted)
  3. Lamparter, C and Winn, L.M. (2014) Tissue-specific effects of valproic acid on DNA repair genes and apoptosis in post-implantation mouse embryos. Toxicol. Sci. 141: 59-67.
  4. Tung, E.W.Y., Philbrook, N.A., Belanger, C.L., Ansari, A. and Winn, L.M. (2014) Benzo[a]pyrene increases DNA double strand break repair in vitro and in vivo: a possible mechanism for benzo[a]pyrene-induced toxicity. Mutation Research – Genetic Toxicology and Environmental Mutagenesis 760: 64-69.
  5. Stokes, S.E. and Winn, L.M. (2014) NK-kB signaling is increased in HD3 cells following exposure to 1,4-benzoquinone: Role of reactive oxygen species and p38-MAPKa. Toxicol. Sci. 137: 303-310.
  6. Philbrook, N.A. and Winn, L.M. (2014) Sub-chronic sulforaphane exposure in CD-1 pregnant mice enhances maternal NADPH quinone oxidoreductase 1 (NQO1) activity and mRNA expression of NQO1, glutathione S-transferase, and glutamate-cysteine ligase: Potential implications for fetal protection against toxicant exposure. Repro. Toxicol. 43: 30-37.
  7. Tung, E. Y.Y., Philbrook, N.A , MacDonald, K.D.D. and Winn, L.M. (2012) DNA double strand breaks and DNA recombination in benzene-metabolite induced genotoxicity. Toxicol. Sci. 126: 569-577.
  8. Philbrook, N.A., Walker, V.K., Afrooz, A.R.M.N, Saleh, N.V. and Winn, L.M. (2011) Investigating the effects of functionalized carbon nanotubes on reproduction and development in Drosophila melanogaster and CD-1 mice. Repro. Toxicol. 32: 442-448.
  9. Philbrook, N.A., Winn, L.M., Afrooz, A.R.M.N, Saleh, N.V. and Walker, V.K. (2011) The effect of TiO2 and Ag nanoparticles on reproduction and development of Drosophila melanogaster and CD-1 mice. Toxicol. Appl. Pharmacol. 257: 429-436.
  10. Tung, E. Y.Y. and Winn, L.M. (2011) Valproic acid increases formation of reactive oxygen species and induces apoptosis in postimplantation embryos: A role for oxidative stress in valproic acid-induced neural tube defects. Mol. Pharmacol. 80: 979-987.
  11. Tung, E. Y.Y. and Winn, L.M. (2011) Valproic acid induced DNA damage increases embryonic p27KIP1 and caspase-3 expression: A mechanism for valproic acid-induced neural tube defects. Repro. Toxicol. 32:255-260.