Research Interests


Research in my lab focuses on anti-tumour immunity and treatment response in ovarian and prostate cancers.


Major themes and areas of research: 

  • Role of Type I Interferon  pathways in sensitivity or resistance to chemotherapy in ovarian cancer using cancer cell lines, in vivo mouse models and patient derived material
  • Immuno-genomic studies to delineate genetic correlates of intra-tumour immune diversity and association with intrinsic and acquired resistance to therapy. 
  • Role of cancer cell intrinsic genetic events and their association with distinct immune microenvironment states in prostate cancer
  • Development of improved non-invasive immune monitoring approaches towards their application as prognostic and predictive indicators for personalized treatment approaches in cancer.
 
Tumour immune interactions//bhsc.queensu.ca/faculty/madhuri-koti/