Selected Publications:

  1. In Utero Dimethadione Exposure Causes Postnatal Disruption in Cardiac Structure and Function in the Rat. Aasa KL, Purssell E, Adams MA, Ozolinš TR. Toxicol Sci. 2014 Sep 19. pii: kfu190. [Epub ahead of print] PMID: 25239635
  2. Regulation and control of AP-1 binding activity in embryotoxicity. Ozolinš TR. Methods Mol Biol. 2012;889:291-303. doi: 10.1007/978-1-61779-867-2_18.PMID: 2266967
  3. Noninvasive high-resolution ultrasound reveals structural and functional deficits in dimethadione-exposed fetal rat hearts in utero.  Purssell E, Weston AD, Thomson JJ, Swanson TA, Brown NA, Ozolinš TR. Birth Defects Res B Dev Reprod Toxicol. 2012 Feb;95(1):35-46. doi: 10.1002/bdrb.20339. Epub 2011 Nov 29. PMID: 22127902 
  4. Co-variation in frequency and severity of cardiovascular and skeletal defects in Sprague-Dawley rats after maternal administration of dimethadione, the N-demethylated metabolite of trimethadione.  Weston AD, Brown NA, Ozolinš TR.
    Birth Defects Res B Dev Reprod Toxicol. 2011 Jun;92(3):206-15. doi: 10.1002/bdrb.20302. Epub 2011 Jun 2. PMID: 21638752 
  5. Not a walk in the park: the ECVAM whole embryo culture model challenged with pharmaceuticals and attempted improvements with random forest design. Thomson J, Johnson K, Chapin R, Stedman D, Kumpf S, Ozolinš TR. Birth Defects Res B Dev Reprod Toxicol. 2011 Apr;92(2):111-21. doi: 10.1002/bdrb.20289. Epub 2011 Mar 2. PMID: 21370399
  6. Cyclophosphamide and the Teratology Society: an awkward marriage.  Ozolins TR.  Birth Defects Res B Dev Reprod Toxicol. 2010 Aug;89(4):289-99. doi: 10.1002/bdrb.20255. Review. PMID: 20803689 
  7. Analysis of the role of the HIF hydroxylase family members in erythropoiesis. Fisher TS, Lira PD, Stock JL, Perregaux DG, Brissette WH, Ozolins TR, Li B. Biochem Biophys Res Commun. 2009 Oct 30;388(4):683-8. doi: 10.1016/j.bbrc.2009.08.058. Epub 2009 Aug 14. PMID: 19683512
  8. Defects in embryonic development of EGLN1/PHD2 knockdown transgenic mice are associated with induction of Igfbp in the placenta. Ozolins TR, Fisher TS, Nadeau DM, Stock JL, Klein AS, Milici AJ, Morton D, Wilhelms MB, Brissette WH, Li B. Biochem Biophys Res Commun. 2009 Dec 18;390(3):372-6. doi: 10.1016/j.bbrc.2009.08.057. Epub 2009 Aug 14. PMID: 19683511