Chapter 5 Faculty Members and Research Areas

Field: Biochemistry and Cell Biology

J. Allingham: Structure and function of kinesin motor proteins

B. Banfield: Molecular and cellular biology

M. G. Blennerhassett: Effects of inflammation on the nerve-smooth muscle relationship of the intestine

S.P.C. Cole: Anti-cancer drug resistance

G. P. Côté: Structure and function of protein kinases

A. Craig: Signal transduction in hematopoietic cells

S. K. Davey: DNA repair mechanisms

P. L. Davies: Antifreeze proteins and calpain

Q. Duan: Pan-omics investigation of biological networks contributing to variable drug response and multifactorial diseases.

N. Ghasemlou: Immune response to nervous system injury and disease

P. A. Greer: Proto-oncogenes in cancer

B. C. Hill: Membrane bioenergetics

Z. Jia: Protein crystallography

G. Jones: Vitamin D metabolism and cytochrome P-450s

F. W. K. Kan: Sperm-egg interaction and reproductive function

A. S. Mak: Podosomes and cell invasion

R. J. Oko: Biology of mammalian sperm components during fertilization

P. M. Petkovich: Retinoic acid signaling

W.C. Plaxton: Plant Biochemistry and Molecular Biology

S. P. Smith: NMR spectroscopy of proteins

V. Walker: Stress genes and the molecular basis of resistance

 

Field: Experimental Medicine

M. A. Adams: Cardiovascular, kidney disease, and sexual dysfunction

J. Allingham: Structure and function of proteins

R. D. Andrew: Electrophysiology of ischemia and head trauma

A. M. Baranchuk: Sleep apnea and cardiac dysfunction

B. M. Bennett: Activation of the cyclic GMP-guanylyl cyclase system

M. J. Beyak: Function of the primary afferent nerves innervating the GI tract and liver

M. G. Blennerhassett: Intestinal inflammation

G. Blohm: Computational neuroscience

A. Craig: Signal transduction in hematopoietic cells

B. A. Croy: Immune cells and pregnancy

Q. Duan: Pan-omics investigation of biological networks contributing to variable drug response and multifactorial diseases.

E. C. Dumont: Neurobiology of pain and addiction

A. Ellis: Allergic diseases

N. Ghasemlou: Immune response to nervous system injury and disease

P. A. Greer: Proto-oncogenes in cancer

A. V. Ferguson: Autonomic control of energy balance

J. T. Fisher: Airway innervation and sensory feedback from the lung

M. F. Fitzpatrick: Sleep and respiration

C. D. Funk: Cardiovascular inflammation

I. Gilron: Clinical pain management

C. H. Graham: Trophoblast and decidual cell interactions; biology of cancer

A. Y. Jin: Stroke, drug design, and neurology

A. Johri: 3D echocardiography, quality control in the echo lab, interventional echocardiography, and Hand Held Cardiac Ultrasound

C. J. Justinich: Pathophysiology and immunology of esophagitis

M. D. Kawaja: Neuroplasticity in the adult mammalian brain

A. E. G. Lomax: Neuroimmune interactions during inflammation

M. D. Lougheed: Symptom perception in asthma

R. J. MacLeod: Non-canonical Wnt signaling in the intestine

N. S. Magoski: Ion channel modulation and neuronal excitability

A. S. Mak: Cell migration and cytoskeleton structure

D. H. Maurice: Phosphodiesterases and vascular function

C. R. Mueller: Role of BRCA1 in breast cancer

D. P. Munoz: Using eye movements to probe brain function and dysfunction

J. A. Neder: Clinical Exercise Physiology of Cardiorespiratory Diseases

C. J. Nicol: Peroxisome proliferator-activated receptors and cancer

D. O’Donnell: Pathophysiology of respiratory diseases

M. Othman: Haemostasis, coagulopathy in cancer and pregnancy complications

S. C. Pang: Cellular pathophysiology in hypertension

M. Pare: Neural basis of cognitive and active vision

C. M. Parker: Cardiopulmonary interactions and mechanisms of dyspnea

W. G. Paterson: Physiology and pathophysiology of the esophagus

E. O. Petrof: Probiotics, microbial-epithelial cell interactions in the gut, and the effects of intestinal bacteria on inflammation

D. P. Redfearn: Novel algorithm development and electrogram analysis

P. K. Rose: Input/output properties of spinal neurons

S. H. Scott: Brain regions involved in motor control and learning

M. Szewczuk: Multimodal approaches targeting tumor cell heterogeneity

C. Tayade: Immune mechanisms in endometriosis and immunology of pregnancy

M. E. Tschakovsky: Cardio-respiratory regulation in exercise

D. A. Van Vugt: Neuroendocrine regulation of the menstrual cycle and appetite

S. J. Vanner: Inflammation and autonomic control of the GI tract

C. A. Ward: Myocardial electrophysiology and reactive oxygen

S. Zhang: Molecular mechanisms of ion channel function in health and heart disease

 

Field: Microbes, Immunity, and Inflammation

B. Banfield: Molecular characterization/analysis of viral proteins important in signal transduction in herpes simplex virus, varicella-zoster virus and pseudorabies virus

S. Basta: Virus-host interactions, focusing on the immunobiology of antigen presenting cells

M. G. Blennerhassett: Effects of inflammation on the nerve-smooth muscle relationship of the intestine

E. B. Carstens: Cellular and molecular biology of viral replication, including roles and interactions of viral and host cell components in viral replication, diversity within a host and host range

A. Daugulis: Cell culture engineering, protein expression, partitioning bioreactors for biosynthesis and bioremediation, bioprocess development, modeling and simulation of bioreactors

A. Ellis: Allergic diseases

K. Gee: Cytokine expression and function regulation during infection and inflammation

N. Ghasemlou: Immune response to nervous system injury and disease

K. F. Jarrell: The unique flagella of methanogenic archaea, from physiological, ultrastructural and genetic aspects

A. Majury: Respiratory viral infections, pandemic influenza, environmental microbiology, epidemiology, zoonotic diseases and public health

N. L. Martin: Understanding how Salmonella typhimurium, a common cause of food poisoning, senses and adapts to changes in environments relevant to infection

J. Martinez-Cajas: Optimization of HIV treatment and better, earlier detection of HIV infection and resistance

E. O. Petrof: Probiotics, microbial-epithelial cell interactions in the gut, and the effects of intestinal bacteria on inflammation

R. K. Poole: Bacterial multidrug efflux pumps and their role in antibiotic and biocide resistance and treatment failure. Role of iron transport in the pathogenesis of Pseudomonas aeruginosa

L. Raptis: Signal transduction in cell transformation and adipocytic differentiation

M. Szewczuk: Role of Toll-like receptors in inflammation and infection

V. Walker: Stress genes and the molecular basis of resistance

W. Wobeser: HIV and epidemiologic studies of Tuberculosis

 

Field: Reproduction and Developmental Sciences

B.A. Croy: Functions, mechanisms of activation and lineage relationships of immune competent cell populations that home to the maternal-fetal interface during mammalian pregnancy

R. Easteal: Learning Modalities, working memory and interactive teaching

C.H. Graham: Cancer progression and the biology of the human placenta

F.W.K. Kan: Regulatory role of glycoproteins secreted by the oviduct in sperm-egg interaction and reproductive functions

M. Koti: Inflammation and chemotherapy resistance in ovarian cancer

L. Mackenzie: Pedagogy in anatomical sciences

R.J. Oko: Developmental biology of specialized mammalian sperm head and tail components and their roles during fertilization

T. R.S. Ozolinš: Developmental toxicology: ventricular septation defects (VDS)

S.C. Pang: Structure and function of the cardiovascular system in health and disease

C. Reifel: The study of human congenital malformations in a collection of human fetuses displaying a wide range of rare developmental anomalies

G.N. Smith: Adverse obstetrical events

C. Tayade:  Understanding the pathophysiology of endometriosis

L. M. Winn: Developmental toxicology

 

Field: Therapeutics, Drug Development, and Human Toxicology

M. A. Adams: Mechanisms underlying the pathogenesis of vascular calcification in chronic kidney disease and development of new therapeutic strategies for prevention and treatment of this condition 

B. M. Bennett: Pharmacology of the nitric oxide/guanylyl cyclase/cGMP signal transduction system

J. F. Brien: Nitric oxide, carbon monoxide and vascular function

S. P.C. Cole: Anti-cancer drug resistance

Q. Duan: Pan-omics investigation of biological networks contributing to variable drug response and multifactorial diseases.

A. Ellis: Allergic diseases

I. Gilron: Clinical management of pain

T. E. Massey: Biochemical and molecular toxicology of the lung

D. H. Maurice: Phosphodiesterases and vascular function

K. Nakatsu: Pharmacology of carbon monoxide and heme oxygenases

C. J. Nicol: Peroxisome proliferator-activated receptor (PPAR)-mediated influence on breast and colon cancer

T. R.S. Ozolinš: Developmental toxicology: ventricular septation defects

E. O. Petrof: Probiotics, microbial-epithelial cell interactions in the gut, and the effects of intestinal bacteria on inflammation

J. N. Reynolds: Neurotoxicology of alcohol

M. Szewczuk: Role of Toll-like receptors in inflammation and infection

L. M. Winn: Developmental toxicology