| BCHM 102/3.0 Introduction to Biochemistry 3L; 1T Chemical principles as applied to biochemistry, human and clinical biochemistry. Winter Term. NOTE: Primarily intended for students in Nursing. Arts & Science students require permission from the program. RECOMMENDATION 4U Chemistry EXCLUSION: No more than 3.0 units from BCHM 102/3.0; BCHM 315/3.0. EXCLUSION: No more than 3.0 units from BCHM 102/3.0; BCHM 316/3.0. EXCLUSION: No more than 1 course from BCHM 102/3.0; BCHM 310/6.0. |
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Principles of protein biochemistry, enzymology, and protein engineering. Metabolism of carbohydrates, amino acids and lipids. Role of coenzymes. Generation and storage of metabolic energy. Principles of regulatory mechanisms, membrane structure and function, hormone action, and cellular signalling. NOTE: Students lacking the prerequisites CHEM 222/3.0 or CHEM 282/3.0 may take these courses as a corequisite with permission from the program. NOTE: Material Fee: estimated cost $45. LEARNING HOURS: 348 (72L; 36Lb; 240P) - lab is alternate weeks PREREQUISITE: (MBIO 218/3.0 and CHEM 222/3.0 and CHEM 223/3.0) or CHEM 282/3.0. EXCLUSION: No more than 6.0 units from BCHM 310/6.0; BCHM 315/3.0; BCHM 316/3.0. EXCLUSION: No more than 1 course from BCHM 102/3.0; BCHM 310/6.0. |
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The application of physical chemistry to biological problems, with an emphasis on arithmetical and algebraic manipulation. Topics include enzyme kinetics, bioenergetics, centrifugation, radioactivity and spectroscopy. LEARNING HOURS: 120 (36L; 84P) PREREQUISITE: Level 3 or above and (CHEM 222/3.0 and CHEM 223/3.0) or CHEM 282/3.0 RECOMMENDATION: BCHM 310/6.0 or (BCHM 315/3.0 and BCHM 316/3.0) and a solid background in physical, analytical and organic chemistry are recommended. |
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Principles of protein biochemistry, enzymology, and protein engineering. NOTE: Students lacking the prerequisites CHEM 222/3.0 or CHEM 282/3.0 may take these courses as a corequisite with permission of the Department. LEARNING HOURS: 120 (36L; 12O; 72P) PREREQUISITE: Level 3 or above and (MBIO 218/3.0 and CHEM 222/3.0 and CHEM 223/3.0) or CHEM 282/3.0. EXCLUSION: No more than 6.0 units from BCHM 310/6.0; BCHM 315/3.0; BCHM 316/3.0. EXCLUSION: No more than 1 course from BCHM 102/3.0; BCHM 310/6.0. |
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Metabolism of carbohydrates, amino acids and lipids. Role of coenzymes. Generation and storage of metabolic energy. Principles of regulatory mechanisms, membrane structure and function, hormone action, and cellular signalling. PREREQUISITE: BCHM 315/3.0. EXCLUSION: No more than 6.0 units from BCHM 310/6.0; BCHM 315/3.0; BCHM 316/3.0. EXCLUSION: No more than 3.0 units from BCHM 102/3.0; BCHM 316/3.0. |
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Application of separation and assay techniques to the study of proteins, metabolism and molecular biology. Attendance required in both terms. Enrolment will be limited because of laboratory constraints, and selection will be based on academic standing. NOTE: Material Fee: estimated cost $60. LEARNING HOURS: 360 (92Lb; 264P) COREQUISITES: BCHM 315/3.0 and BCHM 316/3.0. |
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This course presents an integrated approach to the study of protein function. Topics include proteomic techniques, mass spectrometry, protein purification, imaging, surface plasmon resonance, calorimetry, bioinformatics and protein evolution, protein modifications and processing, interpretation and applications of 3-D structure, and structure-function relationships. NOTE: Offered jointly with BCHM 810/3.0. Students in a LISC or BMCO Plan should contact the program regarding prerequisites and permission to register. PREREQUISITE: Level 4 and (registration in a BCHM Specialization or Major Plan) and (a GPA 2.7 in BCHM 313/3.0, 315/3.0, 316/3.0, 317/3.0, MBIO 218/3.0). |
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This course concentrates on the molecular biology of mammalian models particularly mechanisms involved in human diseases. The human genome project, forensic analysis, DNA diagnostics of human diseases, models of transcriptional and growth regulation and cancer, DNA repair, RNA processing and translation are all discussed. Emphasis on recent findings and course materials will be drawn from current reviews. NOTE: Students in LISC or BMCO Plan should contact the program regarding prerequisites and permission to register. PREREQUISITE: Level 4 and (registration in a BCHM Specialization or Major Plan) and (a GPA 2.7 in BCHM 313/3.0, 315/3.0, 316/3.0, 317/3.0, MBIO 218/3.0). |
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Biochemical research techniques with emphasis on nucleic acids, protein structure and function, regulation of gene expression and metabolic control processes. NOTE: 6.0 unit course offered in the Fall Term. PREREQUISITES: Level 4 and (registration in a BCHM Specialization Plan) and (a GPA 3.3 in BCHM 313/3.0, 315/3.0, 316/3.0, 317/3.0, MBIO 218/3.0). |
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An independent research project by each student in one of the departmental research labs. Evaluation is based on oral presentation, lab performance and a thesis. NOTE: 6.0 unit course offered in the Winter Term. PREREQUISITE: Level 4 and (registration in a BCHM Specialization Plan) and (a GPA 3.3 in BCHM 313/3.0, 315/3.0, 316/3.0, 317/3.0, MBIO 218/3.0). |
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Principles of regulatory mechanisms; regulation of cellular function and growth by oncogenes, growth factors, isoprenoids and steroid hormones. Receptors, second messengers and protein phosphorylation. Correlation of cell ultrastructure with biochemical function. Description of the components, assembly, metabolism and evolution of cellular structures are described. NOTE: Students in a LISC Plan should contact the Department regarding the prerequistes and permission to register. PREREQUISITES: Level 4 and (registration in a BCHM Specialization or Major Plan) and (a GPA 2.7 in BCHM 313/3.0, 315/3.0, 316/3.0, 317/3.0, MBIO 218/3.0). EXCLUSION: No more than 3.0 units from BCHM 432/3.0; BCHM 431/3.0 EXCLUSION: No more than 3.0 units from BCHM 432/3.0; BCHM 433/3.0 |
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Tutorials, assignments and demonstrations in important subjects in biochemistry emphasizing topics of broad interest. Particular emphasis will be paid to the applications of biochemical knowledge and new technologies. NOTE: Students in the BCHM Specialization Plan registered in BCHM 421/6.0 and BCHM 422/6.0 will not be allowed to register in BCHM 441/3.0; Students in the LISC Specialization Plan registered in one of ANAT 499/9.0, CANC 499/9.0, EPID 499/9.0, LISC 499/9.0, MICR 455/6.0, MICR 499/9.0, NSCI 499/9.0, PATH 499/9.0, PHAR 499/9.0 or PHGY 499/9.0 will not be allowed to register in BCHM 441/3.0. PREREQUISITES: Level 4 and (registration in a BCHM Major Plan) and (a GPA 2.7 in BCHM 313/3.0, 315/3.0, 316/3.0, 317/3.0, MBIO 218/3.0). |
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Tutorials, assignments and demonstrations in important subjects in biochemistry emphasizing topics of broad interest. Particular emphasis will be paid to the applications of biochemical knowledge and new technologies. NOTE: Students in the BCHM Major Plan registered in BCHM 441/3.0 will not be allowed to register in BCHM 442/3.0. PREREQUISITES: Level 4 and (registration in a BCHM Specialization Plan) and (a GPA 2.7 in BCHM 313/3.0, 315/3.0, 316/3.0, 317/3.0, MBIO 218/3.0). |
