NSCI 414 - Progress in Neuroanatomy and Neuropharmacology REMOTE
A contemporary and comprehensive assessment of the neurochemical anatomy and neuropharmacology of the mammalianand human nervous systems as they relate to development, function and disease. Topics will include dynamics of neurotransmitter interactions, neuronal drug receptor interactions and second messengers, neurotoxicity associated transmitters and neural growth factors.
NOTE BMCO students should contact the Department regarding prerequisites.
A GPA of 2.5 and (a grade of Bâ in ANAT 312/3.0 or NSCI 323/3.0 or PHAR 340/3.0).
Corequisite: NSCI 324/3.0.
Upon successful completion of this course the student should be able to:
- Recognize the main components of the central/peripheral nervous system and understand how individual neurons work and communicate with one another, and how neurons adapt over time to external stimuli;
- Understand the mechanisms by which drugs alter brain function;
- Understand the sequence of events that commences with the binding of a drug to an initial molecular target and the resulting alteration in the functioning of that target, the influence of that occurrence on the biochemical networks that exist within neurons, the subsequent changes in the output of the neuron, and their consequences for the functioning of circuits within which the targeted neuron;
- Recognize how the brain controls complex autonomic functions such as movement, hormone release, pain, reproduction and sleep/arousal.
- Determine the normal neural mechanisms underlying a particular domain of nervous system functioning and the diseases that affect that domain;
- Understand the influence of drugs on the neural circuits involved in both normal function and specific disease states.
The examination schedule is structured such that there are three blocks within the course. Each block will be examined separately.
Exams #1-3 will consist of multiple-choice and short-answer questions, and each will account for one-third of the final mark.
Exam #3 will be scheduled during the regular exam period.
Learning Hours: 130 (24L;10T;96P)
There is no assigned textbook for this course. Instructors may provide an outline and/or required readings at the beginning of each lecture. Each “Class Discussion” will focus on one or two selected papers by the instructor, and these will be discussed at length. Class participation is strongly encouraged. Students are responsible for lecture material and any assigned readings.