Selected Publications

2016

Gordon C, Rajagopalan N, Riseeuw E, Barber C, Abrams SR, Loewen MC. (2016) Identification of T. aestivum abscisic acid receptors and evidence of their role in Fusarium Head Blight susceptibility. PLoS ONE 11(10): e0164996. doi:10.1371/journal.pone.0164996

Cuperlovich-Culf M, Rajagopalan N, Tulpan D, Loewen MC. (2016) Metabolomics and Cheminformatics analysis of Antifungal Function of Plant Metabolites. Metabolites. 6(4). pii: E31.

Rajagopalan N, Nelson KM, Douglas AF, Jheequt V, Alacorn, IQ, McKenna SA, Surpin M, Loewen MC*, Abrams SR. (2016) Abscisic Acid Analogues That Act as Universal or selective Antagonists of Phytohormone Receptors. Biochemistry. 55:5155-5164. *corresponding author

Rajagopalan, N., Halasz, A., Lu, Y., Liu, E., Monteil-Rivera, F., Loewen, M.C. (2016) Probing allocrite preferences of two naturally occurring variants of the wheat LR34 ABC transporter. Biochem and Cell Biol. 94(5):459-470.

Panwar,V.,McCallum,B.,Jordan,M.,Loewen,M.,Fobert,P.,McCartney,C.,Bakkeren,G.(2016) RNA Silencing Approaches for Identifying Pathogenicity and Virulence Elements Towards Engineering Crop Resistance To Plant Pathogenic Fungi. CAB Reviews 11, 027, pp 1-13.

Buhrow L.M., Cram, D., Tulpan, D., Foroud, N.A., Loewen, M.C. (2016) Exogenous abscisic acid and gibberellic acid elicit opposing effects on Fusarium graminearum infection in wheat. Phytopathology.106:986-996.

Buhrow LM, Clark SM, Loewen MC (2016). Identification of an attenuated barley stripe mosaic virus for the virus-induced gene silencing of pathogenesis-related wheat genes. Plant Methods 12:12.

Choudhary P & Loewen MC (2016) Evidence for a role for S. cerevisiae alpha-arrestin Art1 (Ldb19) in mating projection and zygote formations. Cell Biol Int. 40:83-90.

Choudhary P & Loewen MC (2016) Quantification of mutation-derived bias for alternate mating functionalities of the Saccharomyces cerevisiae Ste2p pheromone receptor. J Biochem. 159:49-58.

2015

Benson, C.L., Kepka, M., Wunschel., C., Rajagopalan, N., Nelson, K.M., Christmann, A., Abrams, S.R., Griill, E., Loewen, M.C. (2015) Abscisic acid analogs as chemical probes for dissection of abscisic acid responses in Arabidopsis thaliana. Phytochemistry. 113:96-107.

Galka MM, Rajagopalan N, Buhrow LM, Nelson KM, Switala J, Cutler AJ, Palmer DR, Loewen PC, Abrams SR, Loewen MC. (2015) Identification of Interactions between Abscisic Acid and Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase. PLoS One.10:e0133033.

Pydi SP, Jaggupill A., Nelson KM, Abrams SR, Bhullar RP, Loewen MC, Chelikani P (2015) Abscisic acid acits as a blocker of the better taste g-protein coupled receptor T2R4. Biochemistry 54:2622-31.

2014

Pydi, S.P., Sobotkiewca, T., Bilakanti, R., Bhullar, R.P., Loewen, M.C., Chelikani, P., (2014) Amino acid derivatives as bitter taste receptor (T2R) blockers. J. Biol. Chem.289:25054-25066.

Dorosh, L., Rajagopalan, N., Loewen, M.C., Stepanova, M. (2014) Molecular mechanisms in the selective basal activation of pyrabactin receptor 1: comparative analysis of mutants. FEBS Open Bio 4:496-509.

2013

Olesya A. Kharenko; Devin Polichuk; Ken M. Nelson; Suzanne R. Abrams; Michele C. Loewen (2013) Identification and characterization of interactions between abscisic acid and human heat shock protein 70 family members J Biochem 154:383-391.

Olesya A. Kharenko, Pooja Choudhary, Michele C. Loewen (2013) Abscisic acid binds to recombinant Arabidopsis thaliana G-protein coupled receptor-type G-protein 1 in Sacaromycese cerevisiae and in vitro. Plant Physiol Biochem 68:32-6.

Lyudmyla Dorosh, Olesya A. Kharenko, Nandahkishore Rajagopalan, Michele C. Loewen, Maria Stepanova (2013)  Molecular mechanisms in the activation of abscisic acid receptor PYR1. PLoS Comput Biol 9(6):e1003114.

Peter C. Loewen, Allison L. Didychuk, Jacek Switala, Rosa Perez-Luque, Ignatio Fita Michele C. Loewen (2013) Structure of Pisum Sativum RUbisco with bound ribulose 1,5-bisphosphate Acta Crystallographica F 69:10-14.

2012

Suzanne R. Abrams, Michele C. Loewen, Jason Boyd, Adrian John Cutler, Yuanzhu Gai, Kenneth, M. Nelson (2012) Inhibitors of a 9-cis epoxycarotenoid dioxygenase. United States Patent US 8,283,481 Issues Oct 9, 2012.

2011

Olesya A. Kharenko, Jason Boyd, Ken M. Nelson, Suzanne, R. Abrams, Michele C. Loewen (2011) Identification and characterization of interactions between abscisic acid and mitochondrial adenine nucleotide translocators. Biochemical Journal437:117-123.

Olesya A. Kharenko, Irina Zaharia, Mike Giblin, Vera Cekic, David Taylor, Don Palmer, Sue R. Abrams & Michele C. Loewen (2011) Abscisic acid metabolism and lipid accumulation of a cell suspension culture of Lesquerella fendleriPlant Cell Tissue and Organ Culture 105:415-422.

2010

Olesya A. Kharenko & Michele C. Loewen (2010) Characterization of the ATP Translocating Properties of the Predicted Arabidopsis thaliana Mitochondrial Adenine Nucleotide Translocator 2. Botany 88:685-690.

2009

Chunhua Shi, Stephanie Kendall, Eric Grote, Susan Kaminskyj, Michele Loewen (2009) N-Terminal Residues of the Yeast Pheromone Receptor, Ste2p, Mediate Mating Events Independently of G1-Arrest Signalling. Journal of Cellular Biochemistry 107:630-638.

Boyd, J., Gai, Y., Melson, K.M., Lukiwski, E., Talbot, J., Loewen, M.K., Owen, S., Zaharia, L.I., Cutler, A.J., Abrams, S.R., Loewen, M.C., (2009) Sesquiterpene-like inhibitors of a 9-cis-epoxycarotenoid dioxygenase regulating abscisic acid biosynthesis in higher plants.  Bioorganic and Medicinal Chemistry 17:2902-2912.

Chunhua Shi, Matthew F. Paige, Jason Maley, Michele C. Loewen (2009) In vitro characterization of ligand-induced oligomerization of the S. cerevisiae G-protein Coupled Receptor, Ste2p. Biochimica et Biophysica Acta. 1790:1-7.