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class="main-content-inner"> <div class="content-main"> <div class="region region-content"> <div id="block-gavias-financial-content" class="block block-system block-system-main-block no-title"> <div class="content block-content"> <!-- Start Display article for teaser page --> <!-- Start Display article for detail page --> <article data-history-node-id="957" about="/index.php/faculty/kimberly-dunham-snary" class="node node-detail node--type-team node--promoted node--view-mode-full clearfix"> <div class="team-single-page"> <div class="team-name clearfix"> <div class="name"> Kimberly Dunham-Snary <span class="heading"> MPS, PhD</span> </div> <!--<div class="line"><span class="one"></span><span class="second"></span><span class="three"></span></div>--> </div> <div class="team-description"></div> <div class="team-info"> <div class="row"> <div class="col-lg-4 col-sm-12 col-xs-12"> <div class="team-image"> <img src="/sites/dbms/files/team/Dunham-Snary_Photo.jpg" alt=" Kimberly Dunham-Snary"> </div> </div> <div class="col-lg-8 col-sm-12 col-xs-12"> <div class="team-contact"> <div class="heading">Position(s)</div> <div class="job"> <div class="field field--name-field-team-position field--type-string field--label-hidden field__items"> <div class="field__item">Assistant Professor</div> <div class="field__item">Tier II Canada Research Chair in Mitochondrial & Metabolic Regulation in Health & Disease</div> </div> </div> <div class="heading">Contact Info</div> <div class="content-inner"> <div class="field field--name-field-team-email field--type-email field--label-hidden field__item"><a href="mailto:Kimberly.DunhamSnary@queensu.ca">Kimberly.DunhamSnary@queensu.ca</a></div> </div> <div class="content-inner"> <div class="field field--name-field-team-contact field--type-string field--label-hidden field__items"> <div class="field__item">Lab website: www.mitometablab.com</div> </div> </div> </div> </div> </div> </div> <hr> <div class="node__content clearfix"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p><strong>Lab website</strong>: <span lang="EN-US"><span><a href="http://www.mitometablab.com"><span lang="EN-CA"><span>www.mitometablab.com</span></span></a></span></span></p> <h3>Academic Experience</h3> <p><span><span><span><span>2015-2020: CIHR and CVN Postdoctoral Fellow (Stephen Archer), Department of Medicine, Queen’s University </span></span></span></span></p> <p><span><span><span><span>2009-2014: PhD in Molecular & Cellular Pathology (Scott Ballinger), Department of Pathology, University of Alabama at Birmingham</span></span></span></span></p> <p><span><span><span><span>2006-2008: MPS in Forensic Science (Robert Shaler), Eberly College of Science, The Pennsylvania State University</span></span></span></span></p> <p><span><span><span><span>2002-2006: B.Sc. (Hons.) in Applied Bio-Molecular Science (Carney Matheson), Faculty of Science & Environmental Studies, Lakehead University</span></span></span></span></p> <h3>Research Interests</h3> <p><span><span><span><span>My laboratory studies cardiovascular and cardiometabolic diseases. Using in vitro and in vivo preclinical models, we investigate the role of mitochondrial genetics and organelle structure in the aetiology and pathophysiology of these complex pathologies. Please visit the lab’s website for more information: </span></span><a href="http://www.mitometablab.com"><span lang="EN-CA"><span>www.mitometablab.com</span></span></a> </span></span></p> <h3>Funding Support</h3> <ul> <li><span><span><span><span>Canadian Institutes for Health Research</span></span></span></span></li> <li><span><span><span><span>New Frontiers Research Fund</span></span></span></span></li> <li><span><span><span><span>Canada Research Chairs</span></span></span></span></li> <li><span><span><span><span>Canada Foundation for Innovation</span></span></span></span></li> <li><span><span><span><span>Banting Research Foundation</span></span></span></span></li> </ul> <h3>Selected Publications</h3> <p><span><span><span><span>Shastry, AM</span></span><span lang="EN-US"><span>, </span></span><strong><span lang="EN-US"><span>Dunham-Snary KJ.</span></span></strong> <span><span>Metabolomics and mitochondrial dysfunction in cardiometabolic disease</span></span><span lang="EN-US"><span>.</span></span> <em><span><span>Life Sci. </span></span></em><span><span>2023 Oct 1:122137.<em> DOI: 10.1016/j.lfs.2023.122137. Online ahead of print.</em></span></span></span></span></p> <p><span><span><span><span>Wilkinson MS</span></span><span lang="EN-US"><span>, </span></span><strong><span lang="EN-US"><span>Dunham-Snary KJ.</span></span></strong> <span><span>Blood-based bioenergetics: a liquid biopsy of mitochondrial dysfunction in disease</span></span><span lang="EN-US"><span>.</span></span><em> </em><em><span><span>Trends Endocrinol Metab. </span></span></em><span><span>2023 Jul 4;S1043-2760(23)00115-7.</span></span></span></span></p> <p><span><span><span><span>DOI: 10.1016/j.tem.2023.06.004.</span></span></span></span></p> <p><span><span><strong><span><span>Dunham-Snary KJ.</span></span></strong><span><span> The haplogroup gap: The ticking time bomb of cardiometabolic disease in developing nations. <em>Open Access Government. </em>2023 Jan;20:142-143. DOI: 10.56367/OAG-037-10518</span></span></span></span></p> <p><span><span><span><span>Mason E</span></span><span lang="EN-US"><span>, Hindmarch CCT, <strong>Dunham-Snary KJ.</strong> Medium-chain acetyl Co-A dehydrogenase deficiency: pathogenesis, diagnosis, and treatment.<em> </em></span></span><em><span><span>Endocrinol Diabetes Metab.</span></span></em><span><span> 2023 Jan;6(1):e385.</span></span></span></span></p> <p><span><span><strong><span><span>Dunham-Snary KJ</span></span></strong><span><span>, Surewaard BGJ, Mewburn JD, Lima PDA, Jones O, Al-Qazazi R, Martin AY, Bentley RET, Kubes P, Archer SL. Mitochondria in human neutrophils mediate killing of <em>staphylococcus aureus</em>. <em>Redox Biol. </em>2022 Feb;49:102225<em>.</em></span></span></span></span></p> <p><span><span><span lang="EN-US"><span>Read A#, Bentley R#, Archer SL, <strong>Dunham-Snary KJ.</strong> Mitochondrial iron-sulfur clusters: Structure, function, and an emerging role in vascular biology. </span></span><span><span>Redox Biol. 2021 Nov;47:102164.</span></span></span></span></p> <p><span><span><strong><span><span>Dunham-Snary KJ,</span></span></strong><span><span> Wu D, Sykes EA, Potus F, Mewburn JD, Charles RL, Eaton P, Sultanian RA, Archer SL. Ndufs2, a core subunit of mitochondrial complex I, is essential for acute oxygen-sensing and hypoxic pulmonary vasoconstriction. <em>Circ Res.</em> 2019 Jun 7;124(12): 1727-1746.</span></span></span></span></p> <p><span><span><strong><span><span>Dunham-Snary KJ</span></span></strong><span><span>, Sandel MW, Sammy MJ, Westbrook DG, Xiao R, McMonigle RJ, Ratcliffe, WF, Penn A, Young ME, Ballinger SW. Mitochondrial - nuclear genetic interaction modulates whole body metabolism, adiposity and gene expression in vivo. <em>EBioMedicine. </em>2018 Oct;36:316-328.</span></span></span></span></p> <p><span><span><strong><span><span>Dunham-Snary KJ</span></span></strong><span><span>, Wu D, Sykes EA, Thakrar A, Parlow LR, Mewburn JD, Parlow JL, Archer SL. Hypoxic Pulmonary Vasoconstriction: From Molecular Mechanisms to Medicine. <em>Chest.</em> 2017 Jan;151(1):181-192.</span></span></span></span></p> <p><span><span><strong><span><span>Dunham-Snary KJ</span></span></strong><span><span>, Hong ZG, Xiong PY, Del Paggio JC, Herr JE, Johri AM, Archer SL. A mitochondrial redox oxygen sensor in the pulmonary vasculature and ductus arteriosus. <em>Pflugers Arch.</em> 2016 Jan;468(1):43-58.</span></span></span></span></p> <p><span><span><strong><span><span>Dunham-Snary KJ</span></span></strong><span><span>, Ballinger SW. GENETICS. Mitochondrial-nuclear DNA mismatch matters. <em>Science.</em> 2015 Sep 25;349(6255):1449-50.</span></span></span></span></p> <p><span><span><strong><span><span>Dunham-Snary KJ</span></span></strong><span><span>, Sandel MW, Westbrook DG, Ballinger SW. A method for assessing mitochondrial bioenergetics in whole white adipose tissues. <em>Redox Biol.</em> 2014 Apr 18;2:656-60.</span></span></span></span></p> <p><span><span><strong><span><span>Dunham-Snary KJ</span></span></strong><span><span>, Ballinger SW. Mitochondrial genetics and obesity: evolutionary adaptation and contemporary disease susceptibility. <em>Free Radic Biol Med.</em> 2013 Dec;65:1229-37.</span></span></span></span></p> <p><strong>Lab Members</strong></p> <p><span><span><span><span>The Dunham-Snary Lab (MitoMetabLab) is currently home to numerous undergraduate and graduate students with backgrounds in cellular and/or molecular biology, life sciences, and other medical and health-related fields. Please check back the lab’s website (<em><a href="http://www.mitometablab.com">www.mitometablab.com</a></em>) for up-to-date information regarding available positions.</span></span></span></span></p> </div> </div> </div> </article> <!-- End Display article for detail page --> </div> </div> </div> </div> </div> </div> <!-- Sidebar Left --> <!-- End Sidebar Left --> <!-- Sidebar Right --> <div class="col-lg-4 col-md-4 col-sm-12 col-xs-12 sidebar sidebar-right theiaStickySidebar"> <div class="sidebar-inner"> <div class="region region-sidebar-right"> <div class="views-element-container block block-views block-views-blockprofiles-block-3" id="block-views-block-profiles-block-3"> <h2 class="block-title" ><span>Faculty</span></h2> <div class="content block-content"> <div><div class="team-grid-2 view-search-inline gva-view view view-profiles view-id-profiles view-display-id-block_3 js-view-dom-id-76f3a6e7a7b017def862efead2d7f9c5b508e9d82250f92f33261cc89721e3b2"> <div class="view-filters"> 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<div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/faith-brennan">Brennan, Faith</a>, Assistant Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/robert-l-campbell">Campbell, Robert L.</a>, Associate Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/chantelle-capicciotti">Capicciotti, Chantelle</a>, Associate Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/lf-carver">Carver, L.F.</a>, Associate Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/edmond-chan">Chan, Edmond</a>, Associate Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/che-colpitts">Colpitts, Che</a>, Assistant Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/andrew-craig">Craig, Andrew</a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/peter-l-davies">Davies, Peter L.</a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/fernanda-de-felice">De Felice, Fernanda</a>, Associate Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/sarah-dick">Dick, Sarah</a>, Assistant Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/nicolle-domnik">Domnik, Nicolle</a>, Assistant Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/qingling-duan">Duan, Qingling</a>, Associate Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/eric-c-dumont">Dumont, Eric C</a>, Associate Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/kimberly-dunham-snary">Dunham-Snary, Kimberly</a>, Assistant Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/alastair-v-ferguson">Ferguson, Alastair V.</a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/jason-gallivan">Gallivan, Jason</a>, Associate Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/katrina-gee">Gee, Katrina</a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/nader-ghasemlou">Ghasemlou, Nader</a>, Associate Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/charles-h-graham">Graham, Charles H.</a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/charlie-hindmarch">Hindmarch, Charlie</a>, Assistant Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/zongchao-jia">Jia, Zongchao</a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/eva-kaufmann">Kaufmann, Eva</a>, Assistant Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/michael-d-kawaja">Kawaja, Michael D.</a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/madhuri-koti">Koti, Madhuri</a>, Associate Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/alan-lomax">Lomax, Alan</a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/leslie-w-mackenzie">MacKenzie, Leslie W.</a>, Associate Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/neil-s-magoski">Magoski, Neil S.</a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/donald-h-maurice">Maurice, Donald H.</a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/christopher-r-mueller">Mueller, Christopher R.</a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/jeanne-mulder">Mulder, Jeanne</a>, Assistant Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/douglas-p-munoz">Munoz, Douglas P.</a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/emily-oby">Oby, Emily</a>, Assistant Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/mark-ormiston">Ormiston, Mark</a>, Associate Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/terence-ozolins">Ozolins, Terence</a>, Associate Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/stephen-c-pang">Pang, Stephen C.</a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/martin-pare">Pare, Martin</a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/p-martin-petkovich">Petkovich, P. Martin</a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/lynne-marie-postovit">Postovit, Lynne-Marie</a>, Professor and Department Head</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/stephen-h-scott">Scott, Stephen H.</a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/amber-simpson">Simpson, Amber</a>, Associate Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/steven-p-smith">Smith, Steven P.</a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/patrick-stroman">Stroman, Patrick </a>, Professor </div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/myron-r-szewczuk">Szewczuk, Myron R.</a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/sebastien-talbot">Talbot, Sebastien</a>, Associate Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/chandrakant-tayade">Tayade, Chandrakant </a>, Professor</div></div> </div> <div class="even-row item"> <div class="views-field views-field-field-team-position"><div class="field-content"><a href="/faculty/christopher-ward">Ward, Christopher A.</a>, Associate Professor</div></div> </div> <div class="even-row item"> <div class="views-field 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