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block-system-breadcrumb-block no-title"> <div class="container"> <div class="breadcrumb-content-main"> <h2 class="page-title hide">Circular Dichroism (CD) Spectrophotometry </h2> <div class=""> <div class="content block-content"> <div class="breadcrumb-links"> <div class="content-inner"> <nav class="breadcrumb " role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">Home</a> <span class=""> / </span> </li> <li> <a href="/research/core-research-facilities">Core Research Facilities</a> <span class=""> / </span> </li> <li> <a href="/research/core-research-facilities/biophysics-core-facility">Biophysics Core Facility</a> <span class=""> / </span> </li> <li> </li> <li> Circular Dichroism (CD) Spectrophotometry </li> <li></li> </ol> </nav> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div role="main" class="main main-page"> <div class="clearfix"></div> <div 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</div> </div> </header> <div class="node__content clearfix"> </div> <div class="gavias-content-blockbuilder"><div class="gavias-blockbuilder-content"> <div class="gbb-row-wrapper"> <div class=" gbb-row bg-size-cover" style="" > <div class="bb-inner default"> <div class="bb-container container"> <div class="row"> <div class="row-wrapper clearfix"> <div class="gsc-column col-lg-12 col-md-12 col-sm-12 col-xs-12"> <div class="column-inner bg-size-cover " > <div class="column-content-inner"> <div class="column-content "><h2>Chirascan</h2></div> <div class="widget gsc-image " > <div class="widget-content"> <img src="https://dbms.queensu.ca/sites/dbms/files/gbb-uploads/Chirascan_Mix-920218.png" alt="" /> </div> </div> <div class="gsc-tabs "> <div class="tabs_wrapper tabs_vertical"> <ul class="nav nav-tabs"> <li class="active"><a data-toggle="tab" href="#uid-as7lq-1"> Description </a></li> <li ><a data-toggle="tab" href="#uid-as7lq-2"> Features </a></li> <li ><a data-toggle="tab" href="#uid-as7lq-3"> Booking & Fees </a></li> </ul> <div class="tab-content"> <div id="uid-as7lq-1" class="tab-pane fade in active"><p>The Chirascan Circular Dichroism (CD) Spectrometer can give insight into the secondary and tertiary structure of proteins, determine the effect of thermal or chemical changes, and help study protein folding and unfolding mechanisms. Used in this way, CD can identify interacting partners of proteins, guide drug testing and development, or simply help optimize protein storage buffer conditions to enhance protein longevity.</p> <p> </p> <p>For more information on these features of CD, please consult the following resource:</p> <p><a href="https://www.photophysics.com/circular-dichroism/">https://www.photophysics.com/circular-dichroism/</a></p></div> <div id="uid-as7lq-2" class="tab-pane fade in "><p>The Chirascan has a temperature-controlled sample chamber for consistent analytical environment and flow cells for secondary (0.1 mm path length) and tertiary (10 mm path length) structure analysis with integrated thermocouples. It can accommodate up to 6 samples or 6 thermal denaturation datasets per run.</p></div> <div id="uid-as7lq-3" class="tab-pane fade in "><p><strong>Fees</strong></p> <table style="width: 58.0106%;"> <tbody> <tr> <td style="width: 32%;"> <p><strong>Service</strong></p> </td> <td style="width: 47.2531%;"> <p><strong>Cost</strong></p> </td> </tr> <tr> <td style="width: 32%;"> <p>Instrument</p> </td> <td style="width: 47.2531%;"> <p>$5/hr up to $50/day</p> </td> </tr> <tr> <td style="width: 32%;"> <p>Training</p> </td> <td style="width: 47.2531%;"> <p>$125/session</p> </td> </tr> </tbody> </table> <p> <strong>Contact and</strong> <strong>Booking</strong></p> <p>Xiaohu Yan (<a href="mailto:yanx@queensu.ca">yanx@queensu.ca</a>; ext. 78265) and Zhilin Chen (<a href="mailto:zc@queensu.ca">zc@queensu.ca</a>; ext. 78238)</p> <p> <strong>Location </strong></p> <p>Botterell Hall, Room 667</p> <p> </p></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> 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