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Circular Dichroism (CD) Spectrophotometry

Chirascan

The Chirascan Circular Dichroism (CD) Spectrometer can give insight into the secondary and tertiary structure of proteins, determine the effect of thermal or chemical changes, and help study protein folding and unfolding mechanisms. Used in this way, CD can identify interacting partners of proteins, guide drug testing and development, or simply help optimize protein storage buffer conditions to enhance protein longevity.

 

For more information on these features of CD, please consult the following resource:

https://www.photophysics.com/circular-dichroism/

The Chirascan has a temperature-controlled sample chamber for consistent analytical environment and flow cells for secondary (0.1 mm path length) and tertiary (10 mm path length) structure analysis with integrated thermocouples. It can accommodate up to 6 samples or 6 thermal denaturation datasets per run.

Fees

Service

Cost

Instrument use (independent use)

$10/hr up to $80/day

Training

$125

*Cost of instrument time + $50/hr Facility Manager time

 

Booking

Booking Calendar: Book Here

 

Location 

Botterell Hall, Room 667

 

Contact 

If you have any questions please contact Xiaohu Yan at yanx@queensu.ca