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Research Showcase - Sam Basta

PhD graduate Dr Andra Banete in Dr Sam Basta's lab has recently provided new insights into the role of IL-4 priming of splenic macrophages on their inflammatory response to Toll-like receptors during the innate immune response.



Macrophage phenotypic plasticity is poorly defined

Splenic macrophages primed with IL-4 show elevated inflammatory mediator production via TLR7/8-STAT6 axis

These results have implications for innate immunity and vaccine development


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