Skip to main content

Research Showcase - Sam Basta

PhD graduate Dr Andra Banete in Dr Sam Basta's lab has recently provided new insights into the role of IL-4 priming of splenic macrophages on their inflammatory response to Toll-like receptors during the innate immune response.

 

Highlights

Macrophage phenotypic plasticity is poorly defined

Splenic macrophages primed with IL-4 show elevated inflammatory mediator production via TLR7/8-STAT6 axis

These results have implications for innate immunity and vaccine development

 

Get the full story here