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BCHM 421/422

SSP Project/Supervisor Selection:

Step 1: You will find all projects listed on our website beginning December 17, 2021. You will have an opportunity to go through them over the holidays to see where your interest is. 

Step 2: Once you return in January, you should arrange to meet with potential supervisors to ask questions about the lab and research project.  (Please note: Supervisors would not be able to guarantee during the discussions that you would selected into their lab).

Step 3: You can go to this document: https://forms.gle/Y66AwpesWJ4KTLcRA to rank your top three selections. The document will open on January 4, 2022 and close at 4pm on January 28, 2022. We will endeavor to do our best to give you one of your choices.  Please only submit your choices once.

Step 4: In the case where more than one person have listed the same supervisor for 1st choices, the supervisor will be given the opportunity to choose. Keep in mind that there is no guarantees or promises given to students in advance of our decision. You will know by February 15, 2022 who your supervisor will be and which project you will be working on.

Step 5: Once final marks in May have been received we will ensure that everyone meets the requirements to be in BCHM 421 and BCHM 422.

PREREQUISITE: Level 4 and (registration in a BCHM Specialization Plan) and (a cumulative GPA of 2.9 in BCHM 313/3.0, BCHM 315/3.0, BCHM 316/3.0, BCHM 317/6.0, BCHM 218/3.0). 

Participating Faculty 2022-2023

SUPERVISOR

PROJECT TITLE

Allingham, John Dissection of the ATPase cycle of kinesin-8 at the microtubule plus end
Capicciotti, Chantelle Investigating Cellular Glyco-Engineering with Sialyltransferases
Chan, Edmond Targeting Mitochondrial fusion in cancer cell metabolism and cell death regulation
Craig, Andrew Developing a co-culture model for testing cancer immunotherapies targeting TGF-β and immune checkpoint inhibitors

Davies, Peter #1

Structure-function relationships in ice-binding proteins

Davies, Peter #2

Structure-function relationships in ice nucleation proteins

Davies, Peter #3 Limb girdle muscular dystrophy mutations and calpain-3 protease binding to titin
Howe, Graeme

Identification and optimization of novel plastic degrading enzymes from thermophilic bacteria

Jia, Zongchao #1

Polyphosphate in bacterial virulence and mammalian physiology

Jia, Zongchao #2

Structural Investigations and Characterization of an Atypical Alpha-Kinase, Eukaryotic Elongation Factor 2 Kinase

Maurice, Donald #1

The Primary Cilium: A Hyper-localized Compartment for cAMP Signaling-1

Maurice, Donald #2 The Primary Cilium: A Hyper-localized Compartment for cAMP Signaling-2
Ormiston, Mark Tracking bone morphogenetic protein signaling for the manipulation of blood vessel growth
Petkovich, Martin Vitamin A regulation of skin barrier formation
Ross, Avena Investigating the biosynthesis of tambjamine natural products
Snedden, Wayne Investigating calcium signal transduction in plants

Participating Faculty 2021-2022

SUPERVISOR

PROJECT TITLE

Capiciotti, Chantelle Developing Antibody-drug conjugate through site-specific Glycoengineering
Chan, Edmond #1 Investigating mitochondrial fusion in cancer cell metabolism and downstream stress responses
Chan, Edmond #2 Mechanisms of SARS-CoV2 in the subversion of mitochondrial anti-viral immunity
Craig, Andrew A novel melanoma subtype defined by chromosome 19 miRNA cluster expression
Craig, Andrew & Allingham, John Developing novel actin-targeting antibody drug conjugates for metastatic cancers

Davies, Peter #1

Antimicrobial strategies by blocking bacterial adhesion

Davies, Peter #2

Structure-function relationships in ice nucleation proteins

Ghasemlou, Nader #1 In silico and in vivo approaches to identify novel pain mediators
Ghasemlou, Nader #2 Neuropeptide control of immune cell recruitment and activation
Howe, Graeme

Engineering a ‘self-sufficient’ Baeyer-Villiger monooxygenase

Jia, Zongchao #1

Structure-guided inhibition of polyphosphate kinases in P. aeruginosa as a novel antivirulence approach

Jia, Zongchao #2

Structure and functional insights into the alpha-kinase eEF2K and its regulation

Mueller, Christopher #1 A blood test for directing Immunotherapy in Lung Cancer
Mueller, Christopher #2 A blood test for Prostate Cancer, replacing PSA
Mueller, Christopher #3 A blood test for Breast Cancer, replacing mammography
Mueller, Christopher #4 A blood test for Pancreatic cancer
Ormiston, Mark Manipulating blood vessel growth in the lung using bone morphogenetic proteins
Ross, Avena Investigating the biosynthesis of tambjamine natural products
Snedden, Wayne Investigating calcium signal transduction in plants