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BCHM 421/422

SSP Project/Supervisor Selection:

Step 1: You will find all projects listed on our website beginning December 21, 2018. You will have an opportunity to go through them over the holidays to see where your interest is. 

Step 2: Once you return in January you are encouraged to meet with potential supervisors if you have questions about the lab and research project.  Supervisors will not be able to guarantee you will be selected to their lab.

Step 3: You can go to this document: https://docs.google.com/forms/d/1VxPqndTe_7XAFVAHx7FbVSQaFcaIeoBYopjWhAgGVEg to rank your top three selections. The document will open on January 2, 2019 and close at noon on January 31, 2019. We will endeavor to do our best to give you one of your choices.  Please only submit your choices once.

Step 4: In the case where more than one person have listed the same supervisor for 1st choices, the supervisor will be given the opportunity to choose.  Keep in mind that there is no guarantees or promises given to students in advance of our decision.   

Step 4: You will know by February 15, 2019 who your supervisor will be and which project you will be working on.

Step 5: Once final marks in May have been received we will ensure that everyone meets the requirements to be in BCHM 421 and BCHM 422. PREREQUISITE: Level 4 and (registration in a BCHM Specialization Plan) and (a GPA of 2.9 in BCHM 313/3.0, BCHM 315/3.0, BCHM 316/3.0, BCHM 317/6.0, BCHM 218/3.0). Final approval will be complete by May 10, 2019.


Participating Faculty 2019-2020:

SUPERVISOR

PROJECT TITLE

Abraham, Sheela #1

Extracellular Vesicle Biogenesis in Chronic Myeloid Leukaemia

Abraham, Sheela #2

How extracellular vesicles effect stem cell function in Chronic Myeloid Leukaemia

Allingham, John

Investigating the roles of kinesin motors in genome plasticity of Candida albicans

Capicciotti, Chantelle

Investigating Glycan-Protein Interactions in Cells with Photo-Crosslinking Probes

Chan, Edmond #1

Regulation of mitochondria dynamics in cancer cells

Chan, Edmond #2

Role for mitochondria dynamics in cancer cell growth

Craig, Andrew

Defining targets of tumour suppressor microRNAs in malignant melanoma

Craig, Andrew & Allingham, John

Developing novel actin-targeting antibody drug conjugates for metastatic cancers

Davies, Peter #1

 Discovery of new ligand-binding domains in bacterial adhesins

Davies, Peter #2

 Discovery and characterization of new antifreeze proteins

Davies, Peter #3

Structure-function relationships in ice nucleation proteins

Davies, Peter #4

Structure, function and inhibition of the calcium-activated calpain-3 protease

Ghasemlou, Nader #1

Profiling circadian rhythms in sensory neuron

Ghasemlou, Nader #2

Dissecting the inflammatory component of spinal cord injury pain

Jia, Zongchao #1

Structure-guided inhibition of polyphosphate kinase in P. aeruginosa as a novel antivirulence approach

Jia, Zongchao #2

Polyphosphate biosynthesis as a virulence factor determinant in multi-drug resistant bacterial pathogens

Mueller, Christopher #1

A blood test for directing Immunotherapy in Lung Cancer

Mueller, Christopher #2

A blood test for Prostate Cancer, replacing PSA

Mueller, Christopher #3

A blood test for Breast Cancer, replacing mammography

Ormiston, Mark

Examining the impact of non-coding RNAs on the phenotype and function of pulmonary endothelial cells following silencing of the bone morphogenetic protein type II receptor

Plaxton, William

Molecular, regulatory, and functional properties of key enzymes of plant carbohydrate and phosphate metabolism

Ross, Avena

Genome Guided Discovery of Marine Natural Products

Smith, Steven

Engineering designer enzyme complexes for directed production of biomass-based high-value chemicals

Snedden, Wayne

Investigating calcium signal transduction in plants

Wu, Gang & Smith, Steve

Synthesis of 17O-labeled amino acids and their incorporation into proteins

Zechel, David #1

Biosynthesis of a Fluorinated Natural Product in Streptomyces calvus

Zechel, David #2

The mechanisms and substrate specificities of the phosphonate degrading enzymes PhnY and PhnZ

 

Faculty 2018-2019:

SUPERVISOR

PROJECT TITLE

Allingham, John

Understanding and targeting kinesin motors in invasive human fungal pathogens

Chan, Edmond

Regulation of mitochondria dynamics in cancer cells

Côté, Graham

Functional and structural studies on the α-kinase family of protein kinases

Craig, Andrew

Defining targets of tumour suppressor microRNAs in malignant melanoma

Davies, Peter #1

Discovery of new ligand-binding domains in bacterial adhesins

Davies, Peter #2

Discovery and characterization of new antifreeze proteins

Davies, Peter #3

Engineering bacterial adhesins to have new binding affinities

Davies, Peter #4

Structure, function and inhibition of the calcium-activated calpain-3 protease

Funk, Colin

Arginase in Health and Disease

Ghasemlou, Nader

Profiling circadian rhythms in sensory neurons

Jia, Zongchao #1

Structure and functional characterization of eukaryotic elongation factor 2 kinase

Jia, Zongchao #2

Structure-based disruption of Type 2 secretion system of Pseudomonas aeruginosa for development of antibiotics

Lillicrap, David

Extracellular role of the von Willebrand factor propeptide in Hemostasis

Mueller, Christopher #1

A blood test for Lung Cancer

Mueller, Christopher #2

A blood test for Pancreatic Cancer

Ormiston, Mark

High throughput screening of inhibitory peptides targeting the interaction of BMP9 with the Activin type II receptor

Petitjean, Anne

Refining guanine quadruplex binders

Petrof, Elaine

Study of human, defined microbial communities for the treatment of Clostridium difficile infections.

Plaxton, William

Plant Biochemistry & Molecular Biology

Ross, Avena

Isolation and Investigation fo the Biosynthesis of Natural Products from marine bacteria

Smith, Steven

Structural and functional analyses of transcriptional networks associated with B-cell development and cancer

Smith, Steven #2

Engineering designer enzyme complexes for directed production of biomass-based high-value chemicals

Snedden, Wayne

Investigating calcium signal transduction in plants

Walia, Jagdeep

Assessing the role of GM2A antagonism in causation of atherosclerosis

Zechel, David #1

The mechanisms and substrate specificities of the phosphonate degrading enzymes PhnY and PhnZ

Zechel, David #2

Biosynthesis of a Fluorinated Natural Product in Streptomyces calvus