PHAR 416 - Xenobiotic Disposition and Toxicity
An advanced study of chemical disposition and toxicity. Topics include toxicokinetics, biotransformation, metabolite-mediated toxicity, free radicals, the mechanism of action of toxicants, effects of toxicants on organ systems and a detailed examination of selected toxic agents.
NOTE BCHM, BIOL and BMCO students should contact the department for permission to register in this course.
(PHAR 340/3.0 or BCHM 310/9.0 or BCHM 316/3.0) and (Level 4 and (registration in a LISC Specialization or Major Plan or ELSC Specialization Plan) and (a GPA of 2.5).
Problem sets (2): 12.5% each, 25% of final grade
Mid-term examination (in class): 25% of final grade
Final examination (3 hours): 50% of final grade
All exams will be a combination of multiple-choice and short-answer/essay formats, and will cover material from all lectures.
3 hours in class per week. Students can expect to spend approximately 10 hours per week on this course.
Casarett and Doull's Toxicology, 8th edition: C.D. Klaasen (ed)., McGraw-Hill, 2013