Panchenko | Biomedical and Molecular Sciences | School of Medicine | Queen's University

Anna Panchenko PhD

Anna Panchenko

Position(s)

Professor

Canada Research Chair (Tier 1)

Contact Info

anna.panchenko@queensu.ca

Botterell Hall, 9th Floor

We study the causes of disease progression, with a specific focus on cancer, in order to identify which extrinsic and intrinsic factors can contribute to disease mutation occurrence in DNA, as well as to discover molecular mechanisms of how these mutations can affect proteins, protein interactions, and dynamical behavior of chromatin. We apply and design computational methods that integrate hypothesis- and data- driven approaches, including machine learning, molecular modeling and molecular dynamics simulations. We work in close collaboration with many experimental groups and use experimental data ranging from hydroxyl radical footprinting, chemical crosslinking to cryo- electron microscopy to guide us in designing new hybrid approaches. From a practical point of view, this can provide predictive power for the behavior of the system in response to disease and offer experimental leads for identifying driver mutations and genes, and for designing drugs that affect protein interactions and pathways.

Link to Panchenko Lab

Faculty

Abraham, Sheela, Associate Professor

Adams, Michael A., Professor

Allingham, John, Professor

Andrew, R. David, Professor

Banfield, Bruce W, Professor

Basta, Sam, Professor

Blohm, Gunnar, Professor

Boehnke, Susan, Associate Professor

Brennan, Faith, Assistant Professor

Campbell, Robert L., Associate Professor

Capicciotti, Chantelle, Assistant Professor

Carver, L.F., Associate Professor

Chan, Edmond, Associate Professor

Colpitts, Che, Assistant Professor

Craig, Andrew, Professor

Davies, Peter L., Professor

De Felice, Fernanda, Associate Professor

Dick, Sarah, Assistant Professor

Domnik, Nicolle, Assistant Professor

Duan, Qingling, Associate Professor

Dumont, Eric C, Associate Professor

Dunham-Snary, Kimberly, Assistant Professor

Ferguson, Alastair V., Professor

Gallivan, Jason, Associate Professor

Gee, Katrina, Professor

Ghasemlou, Nader, Associate Professor

Graham, Charles H., Professor

Hindmarch, Charlie, Assistant Professor

Jia, Zongchao, Professor

Jones, Glenville, Professor

Kan, Frederick W.K., Professor

Kaufmann, Eva, Assistant Professor

Kawaja, Michael D., Professor

Koti, Madhuri, Associate Professor

Lomax, Alan, Professor

MacKenzie, Leslie W., Associate Professor

Magoski, Neil S., Professor

Maurice, Donald H., Professor

Mueller, Christopher R., Professor

Mulder, Jeanne, Assistant Professor

Munoz, Douglas P., Professor

Oby, Emily, Assistant Professor

Ormiston, Mark, Associate Professor

Ozolins, Terence, Associate Professor

Pang, Stephen C., Professor

Pare, Martin, Professor

Petkovich, P. Martin, Professor

Postovit, Lynne-Marie, Professor and Department Head

Reynolds, James N., Professor

Scott, Stephen H., Professor

Simpson, Amber, Associate Professor

Smith, Steven P., Professor

Stroman, Patrick , Professor

Szewczuk, Myron R., Professor

Talbot, Sebastien, Associate Professor

Tayade, Chandrakant , Professor

Ward, Christopher A., Associate Professor

Winn, Louise M., Professor

Zhang, Shetuan, Professor