BCHM 313 - Molecular Biochemistry | Biomedical and Molecular Sciences | School of Medicine

BCHM 313 - Molecular Biochemistry

Winter 2025 (On-Campus)

Year 3

9-10 hours/week

3 units

Available

On-Campus Course

This course will provide an in depth view of the molecular mechanisms controlling how genes are organized, regulated and expressed in mammalian cells. Once you understand how proteins are made, you will learn a variety of approaches to visualize and measure proteins and enzymatic activities in mammalian cells.

Prerequisites

Level 3 or above and BCHM 315/3.0

Learning Outcomes

Describe the physical and functional properties of the human genome
Explain how epigenetic regulation relates to gene expression
Describe how RNA processing occurs normally and explain how diseases can be linked to aberrant processing
Describe the process and control of mRNA translation
Explain how microRNAs control gene expression
Describe how mRNA vaccines were developed to prevent COVID-19
Describe experimental procedures that can be used to detect the interactions of proteins and nucleic acids both in the test tube (in vitro) and within cells (in vivo)
Describe experimental procedures that can be used to measure the binding affinity of macromolecules
Explain the advantages and limitations of X-ray crystallography and cryo-electron microscopy for studying the structures of proteins, nucleic acids and their complexes
Explain the significance of enzyme activity and enzyme inhibition measurements

Evaluations

Unit quizzes (5) 10%
Assignments (x2, 10% each) 20%
Midterm exam 20%
Group presentation 10%
Final exam 40%

Time Commitment

120 learning hours

BCHM 313 - Molecular Biochemistry

BCHM 313 - Molecular Biochemistry

Prerequisites

Learning Outcomes

Evaluations

Time Commitment

Undergraduate Courses