BCHM 410 / BMED 810 - Protein Structure and Function | Biomedical and Molecular Sciences | School of Medicine

BCHM 410 / BMED 810 - Protein Structure and Function

Fall 2024 (On-Campus)

Year 4

3 units

Available

On-Campus Course

Course Description:

Theories and applications of protein structure determination techniques will be taught. The main focus is on NMR and X-ray crystallography. The course will also cover interpretation and applications of protein 3-D structure, structure-function relationships, structural classification, structural genomics, protein folding, structure-based drug design.

Students (in groups) will be given the opportunities to present and discuss relevant research papers throughout the semester.

Course Objectives:

The main goal of this course is to help the students to integrate what they have learned in the Biochemistry / Life Sciences undergraduate programs to have a better appreciation of how proteins function and gain better understanding of structure-function relationship.

Prerequisites

([Level 4 or above and registration in the BCHM Specialization or Major Plan] and [a minimum GPA of 2.50 in BCHM 218/3.0; BCHM 313/3.0; BCHM 315/3.0; BCHM 316/3.0; BCHM 317/6.0]) or ([Level 4 or above and registration in the LISC Specialization or Major Plan] and [a minimum GPA of 2.50 in BCHM 218/3.0 and [BCHM 310/9.0 or [BCHM 315/3.0 and BCHM 316/3.0]).

Evaluations

Students will be evaluated by their performance in:

1) One mid-term examination (25%);

2) Student group presentations/discussions which also include questions and answers (25%);

3) Final examination (50%).

Total 100%.

Textbooks and Materials

There is no required textbooks for this course. All lecture notes in Power Point format will be available to students. Many of the lecture materials are generated from published research papers and review articles available in PubMed. If appropriate, references will be given in lecture notes.

Grading Method

Queen’s Official Grade Conversion Scale

Grade Numerical Course Average (Range)

A+ 90-100

A 85-89

A- 80-84

B+ 77-79

B 73-76

B- 70-72

C+ 67-69

C 63-66

C- 60-62

D+ 57-59

D 53-56

D- 50-52

F 49 and below