Education
DVM, Justus-Liebig-University Giessen, Germany, 2006-2012
PhD in Immunology, Paul Ehrlich Institute, Langen, Germany, and Justus-Liebig-University Giessen, Germany, 2012-2016
Postdoctoral Fellowship in Immunology, McGill University, Montreal, Canada, 2016-2022
Research Interests
Trained Immunity in Infection, Vaccination, and Asthma
Selected Publications
Kaufmann E*, Sanz J*, Dunn JL*, Khan N, Mendonca LE, Pacis A, Tzelepis F, Pernet E, Dumaine A, Grenier JC, Mailhot-Léonard F, Ahmed E, Belle J, Besla R, Mazer B, King IL, Nijnik A, Robbins CS, Barreiro LB, Divangahi M. (2018) BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis. Cell 172:176–190
Divangahi M, Khan N, Kaufmann E. (2018) Beyond Killing Mycobacterium tuberculosis: Disease Tolerance. Front. Immunol. 9:2976
Khan N*, Downey J*, Sanz J, Kaufmann E, Blankenhaus B, Pacis A, Pernet E, Ahmed E, Cardoso S, Nijnik A, Mazer BD, Sassetti C, Behr MA, Soares MP, Barreiro LB, Divangahi M. (2020) M. tuberculosis reprograms Hematopoietic Stem Cells to limit Myelopoiesis and impair Trained Immunity. Cell 183:752-770
Divangahi M, Aaby P, Abdul Khader S, Barreiro LBB, Bekkering S, Chavakis T, van Crevel R, Curtis N, DiNardo AR, Dominguez-Andres J, Duivenwoorden R, Fanucchi S, Fayad Z, Fuchs E, Hamon M, Jeffrey KL, Khan N, Joosten LAB, Kaufmann E, Latz E, Matarese G, van der Meer JWM, Mhlanga M, Moorlag SJCFM, Mulder WJM, Naik S, Novakovic B, O’Neill L, Ochando J, Ozato K, Riksen NP, Sauerwein R, Sherwood E, Schlitzer A, Schultze JL, Sieweke M, Stabell-Benn C, Stunnenberg H, Sun J, van de Veerdonk FL, Weiss S, Williams D, Xavier R, Netea MG. (2021) Trained Immunity, Tolerance, Priming and Differentiation: Distinct Immunological Processes. Nature Immunol. 22:2-6.
Kaufmann E, Landekic M, Downey J, Chronopoulos J, Teimouri Neyhad S, Tran K, Vinh DC, Barreiro LB, Divangahi M. (2022) Lack of evidence for intergenerational inheritance of immune resistance to infections. Nat Immunol. 23:203-207
Kaufmann E*, Khan N*, Tran KA, Ulndreaj A, Pernet E, Fontes G, Lupien A, Desmeules P, McIntosh F, Abow A, Moorlag SJCFM, Debisarun P, Mossman K, Banerjee A, Karo-Atar D, Sadeghi M, Mubareka S, Vinh DC, King IL, Robbins CS, Behr MA, Netea MG, Joubert P, Divangahi M. (2022) BCG vaccination provides protection against IAV but not SARS-CoV-2. Cell Rep. 38:110502
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Lab Members
Gabriella Stefan
Vidthiya Jeyanathan
Conrad Pietrzak
Lubnaa Hossenbaccus (co-supervised)
Makena Sceeles
Sarah Hopkins