Researchers in this field employ interdisciplinary methods to explore the processes responsible for both the normal and diseased state. This includes the mechanisms underlying disorders of the cardiovascular, gastrointestinal, nervous, respiratory, and urogenital systems, as well as cancer. Molecular, cellular- and/or systems-based approaches are used to investigate cellular or animal models of disease as well as patient populations.
Faculty
S. Abraham: Haematopoietic and cancer stem cell biology
M. A. Adams: Cardiovascular, kidney disease, and sexual dysfunction
J. Allingham: Structure and function of proteins
R. D. Andrew: Electrophysiology of ischemia and head trauma
A. M. Baranchuk: Sleep apnea and cardiac dysfunction
B. M. Bennett: Activation of the cyclic GMP-guanylyl cyclase system
M. J. Beyak: Function of the primary afferent nerves innervating the GI tract and liver
M. G. Blennerhassett: Intestinal inflammation
G. Blohm: Computational neuroscience
A. Craig: Signal transduction in hematopoietic cells
B. A. Croy: Immune cells and pregnancy
Q. Duan: Pan-omics investigation of biological networks contributing to variable drug response and multifactorial diseases.
E. C. Dumont: Neurobiology of pain and addiction
A. Ellis: Allergic diseases
A. V. Ferguson: Autonomic control of energy balance
J. T. Fisher: Airway innervation and sensory feedback from the lung
M. F. Fitzpatrick: Sleep and respiration
J. R. Flanagan: Visual motor control of grasping
L. Flynn: Tissue engineering and adipose-derived stem cells
A. B. Froese: Allergies, acid reflux, and inflammation
C. D. Funk: Cardiovascular inflammation
N. Ghasemlou: Immune response to nervous system injury and disease
I. Gilron: Clinical pain management
C. H. Graham: Trophoblast and decidual cell interactions; biology of cancer
P. A. Greer: Proto-oncogenes in cancer
A. Y. Jin: Stroke, drug design, and neurology
A. Johri: 3D echocardiography, quality control in the echo lab, interventional echocardiography, and Hand Held Cardiac Ultrasound
C. J. Justinich: Pathophysiology and immunology of esophagitis
M. D. Kawaja: Neuroplasticity in the adult mammalian brain
A. E. G. Lomax: Neuroimmune interactions during inflammation
M. D. Lougheed: Symptom perception in asthma
R. J. MacLeod Non-canonical Wnt signaling in the intestine
N. S. Magoski: Ion channel modulation and neuronal excitability
A. S. Mak: Cell migration and cytoskeleton structure
D. H. Maurice: Phosphodiesterases and vascular function
C. R. Mueller: Role of BRCA1 in breast cancer
D. P. Munoz: Using eye movements to probe brain function and dysfunction
C. J. Nicol: Peroxisome proliferator-activated receptors and cancer
D. O’Donnell: Pathophysiology of respiratory diseases
M. Othman: Haemostasis, coagulopathy in cancer and pregnancy complications
S. C. Pang: Cellular pathophysiology in hypertension
M. Pare: Neural basis of cognitive and active vision
C. M. Parker: Cardiopulmonary interactions and mechanisms of dyspnea
W. G. Paterson: Physiology and pathophysiology of the esophagus
E. O. Petrof: Probiotics, microbial-epithelial cell interactions in the gut, and the effects of intestinal bacteria on inflammation
D. P. Redfearn: Novel algorithm development and electrogram analysis
F. Rivest: Mathematical foundation of artificial and natural learning
P. K. Rose: Input/output properties of spinal neurons
S. H. Scott: Brain regions involved in motor control and learning
M. Szewczuk: Multimodal approaches targeting tumor cell heterogeneity
C. Tayade: Immune mechanisms in endometriosis and immunology of pregnancy
M. E. Tschakovsky: Cardio-respiratory regulation in exercise
D. A. Van Vugt: Neuroendocrine regulation of the menstrual cycle and appetite
S. J. Vanner: Inflammation and autonomic control of the GI tract
C. A. Ward: Myocardial electrophysiology and reactive oxygen
S. Zhang: Molecular mechanisms of ion channel function in health and heart disease