Chapter 5 Faculty Members and Research Areas
Field: Biochemistry and Cell Biology
S. Abraham: Haematopoietic and cancer stem cell biology
J. Allingham: Structure and function of kinesin motor proteins
B. Banfield: Molecular and cellular biology of viruses
M. G. Blennerhassett: Effects of inflammation on the nerve-smooth muscle relationship of the intestine
E.Y.W. Chan: Regulation of the autophagy/mitophagy stress response pathway
S.P.C. Cole: Anti-cancer drug resistance
G. P. Côté: Structure and function of protein kinases
A. Craig: Signal transduction in hematopoietic cells
S. K. Davey: DNA repair mechanisms
P. L. Davies: Antifreeze proteins and calpain
Q. Duan: Pan-omics investigation of biological networks contributing to variable drug response and multifactorial diseases.
N. Ghasemlou: Immune response to nervous system injury and disease
P. A. Greer: Proto-oncogenes in cancer
B. C. Hill: Membrane bioenergetics
Z. Jia: Protein crystallography
G. Jones: Vitamin D metabolism and cytochrome P-450s
F. W. K. Kan: Sperm-egg interaction and reproductive function
A. S. Mak: Podosomes and cell invasion
R. J. Oko: Biology of mammalian sperm components during fertilization
P. M. Petkovich: Retinoic acid signaling
W.C. Plaxton: Plant biochemistry and metabolism
S. P. Smith: NMR spectroscopy of proteins
V. Walker: Stress genes and the molecular basis of resistance
Field: Experimental Medicine
S. Abraham: Haematopoietic and cancer stem cell biology
M. A. Adams: Cardiovascular, kidney disease, and sexual dysfunction
J. Allingham: Structure and function of proteins
R. D. Andrew: Electrophysiology of ischemia and head trauma
A. M. Baranchuk: Sleep apnea and cardiac dysfunction
B. M. Bennett: Activation of the cyclic GMP-guanylyl cyclase system
M. J. Beyak: Function of the primary afferent nerves innervating the GI tract and liver
M. G. Blennerhassett: Intestinal inflammation
G. Blohm: Computational neuroscience
A. Craig: Signal transduction in hematopoietic cells
B. A. Croy: Immune cells and pregnancy
Q. Duan: Pan-omics investigation of biological networks contributing to variable drug response and multifactorial diseases.
E. C. Dumont: Neurobiology of pain and addiction
A. Ellis: Allergic diseases
A. V. Ferguson: Autonomic control of energy balance
J. T. Fisher: Airway innervation and sensory feedback from the lung
M. F. Fitzpatrick: Sleep and respiration
J. R. Flanagan: Visual motor control of grasping
L. Flynn: Tissue engineering and adipose-derived stem cells
A. B. Froese: Allergies, acid reflux, and inflammation
C. D. Funk: Cardiovascular inflammation
N. Ghasemlou: Immune response to nervous system injury and disease
I. Gilron: Clinical pain management
C. H. Graham: Trophoblast and decidual cell interactions; biology of cancer
P. A. Greer: Proto-oncogenes in cancer
A. Y. Jin: Stroke, drug design, and neurology
A. Johri: 3D echocardiography, quality control in the echo lab, interventional echocardiography, and Hand Held Cardiac Ultrasound
C. J. Justinich: Pathophysiology and immunology of esophagitis
M. D. Kawaja: Neuroplasticity in the adult mammalian brain
A. E. G. Lomax: Neuroimmune interactions during inflammation
M. D. Lougheed: Symptom perception in asthma
R. J. MacLeod Non-canonical Wnt signaling in the intestine
N. S. Magoski: Ion channel modulation and neuronal excitability
A. S. Mak: Cell migration and cytoskeleton structure
D. H. Maurice: Phosphodiesterases and vascular function
C. R. Mueller: Role of BRCA1 in breast cancer
D. P. Munoz: Using eye movements to probe brain function and dysfunction
C. J. Nicol: Peroxisome proliferator-activated receptors and cancer
D. O’Donnell: Pathophysiology of respiratory diseases
M. Othman: Haemostasis, coagulopathy in cancer and pregnancy complications
S. C. Pang: Cellular pathophysiology in hypertension
M. Pare: Neural basis of cognitive and active vision
C. M. Parker: Cardiopulmonary interactions and mechanisms of dyspnea
W. G. Paterson: Physiology and pathophysiology of the esophagus
E. O. Petrof: Probiotics, microbial-epithelial cell interactions in the gut, and the effects of intestinal bacteria on inflammation
D. P. Redfearn: Novel algorithm development and electrogram analysis
F. Rivest: Mathematical foundation of artificial and natural learning
P. K. Rose: Input/output properties of spinal neurons
S. H. Scott: Brain regions involved in motor control and learning
M. Szewczuk: Multimodal approaches targeting tumor cell heterogeneity
C. Tayade: Immune mechanisms in endometriosis and immunology of pregnancy
M. E. Tschakovsky: Cardio-respiratory regulation in exercise
D. A. Van Vugt: Neuroendocrine regulation of the menstrual cycle and appetite
S. J. Vanner: Inflammation and autonomic control of the GI tract
C. A. Ward: Myocardial electrophysiology and reactive oxygen
S. Zhang: Molecular mechanisms of ion channel function in health and heart disease
Field: Microbes, Immunity, and Inflammation
B. Banfield: Molecular characterization/analysis of viral proteins important in signal transduction in herpes simplex virus, varicella-zoster virus and pseudorabies virus
S. Basta: Virus-host interactions, focusing on the immunobiology of antigen presenting cells
M. G. Blennerhassett: Effects of inflammation on the nerve-smooth muscle relationship of the intestine
E. B. Carstens: (Retired - no longer accepting new students) Cellular and molecular biology of baculovirus replication, including function and interaction of virus and host cell proteins in virus replication
A. Daugulis: Cell culture engineering, protein expression, partitioning bioreactors for biosynthesis and bioremediation, bioprocess development, modeling and simulation of bioreactors
A. Ellis: Allergic diseases
K. Gee: Cytokine expression and function regulation during infection and inflammation
N. Ghasemlou: Immune response to nervous system injury and disease
K. F. Jarrell: The unique flagella of methanogenic archaea, from physiological, ultrastructural and genetic aspects
A. Majury: Respiratory viral infections, pandemic influenza, environmental microbiology, epidemiology, zoonotic diseases and public health
N. L. Martin: Understanding how Salmonella typhimurium, a common cause of food poisoning, senses and adapts to changes in environments relevant to infection
J. Martinez-Cajas: Optimization of HIV treatment and better, earlier detection of HIV infection and resistance
E. O. Petrof: Probiotics, microbial-epithelial cell interactions in the gut, and the effects of intestinal bacteria on inflammation
R. K. Poole: Bacterial multidrug efflux pumps and their role in antibiotic and biocide resistance and treatment failure. Role of iron transport in the pathogenesis of Pseudomonas aeruginosa
L. Raptis: Signal transduction in cell transformation and adipocytic differentiation
M. Szewczuk: Role of Toll-like receptors in inflammation and infection
V. Walker: Stress genes and the molecular basis of resistance
W. Wobeser: HIV and epidemiologic studies of Tuberculosis
Field: Reproduction and Developmental Sciences
B.A. Croy: Functions, mechanisms of activation and lineage relationships of immune competent cell populations that home to the maternal-fetal interface during mammalian pregnancy
R. Easteal: Learning Modalities, working memory and interactive teaching
C.H. Graham: Cancer progression and the biology of the human placenta
F.W.K. Kan: Regulatory role of glycoproteins secreted by the oviduct in sperm-egg interaction and reproductive functions
M. Koti: Inflammation and chemotherapy resistance in ovarian cancer
L. Mackenzie: Pedagogy in anatomical sciences
R.J. Oko: Developmental biology of specialized mammalian sperm head and tail components and their roles during fertilization
T.R.S. Ozolins: Developmental toxicology: ventricular septation defects (VDS)
S.C. Pang: Structure and function of the cardiovascular system in health and disease
C. Reifel: The study of human congenital malformations in a collection of human fetuses displaying a wide range of rare developmental anomalies
G.N. Smith: Adverse obstetrical events
C. Tayade: Understanding the pathophysiology of endometriosis
L. M. Winn: Developmental toxicology
Field: Therapeutics, Drug Development, and Human Toxicology
M. A. Adams: Mechanisms underlying the pathogenesis of vascular calcification in chronic kidney disease and development of new therapeutic strategies for prevention and treatment of this condition
B. M. Bennett: Pharmacology of the nitric oxide/guanylyl cyclase/cGMP signal transduction system
J. F. Brien: Nitric oxide, carbon monoxide and vascular function
S. P.C. Cole: Anti-cancer drug resistance
A. Ellis: Allergic diseases
I. Gilron: Clinical management of pain
T. E. Massey: Biochemical and molecular toxicology of the lung
D. H. Maurice: Phosphodiesterases and vascular function
K. Nakatsu: Pharmacology of carbon monoxide and heme oxygenases
C. J. Nicol: Peroxisome proliferator-activated receptor (PPAR)-mediated influence on breast and colon cancer
T. R.S. Ozolinš: Developmental toxicology: ventricular septation defects
E. O. Petrof: Probiotics, microbial-epithelial cell interactions in the gut, and the effects of intestinal bacteria on inflammation
J. N. Reynolds: Neurotoxicology of alcohol
M. Szewczuk: Role of Toll-like receptors in inflammation and infection
L. M. Winn: Developmental toxicology